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Interrupting the Infection Cycle of Ebola Viruses

A Freiburg research team has discovered the basis for studying the spread of Ebola viruses. Pharmacologist Prof. Dr. Norbert Klugbauer explains the new findings in a video.




February 2015

A German-American research team has succeeded in identifying channels in intracellular membranes that play a key role in virus transport. These channels can be blocked with an active ingredient that stopped the infection in an animal model. The teams led by the Freiburg pharmacologist Prof. Dr. Norbert Klugbauer published their findings in the current issue of the journal Science.

The researcher from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg explains in the video how he blocks channels in cellular vesicles to interrupt the infection cycle of Ebola viruses.




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Prof. Dr. Norbert Klugbauer

Norbert Klugbauer is a research group leader at the Institute of Experimental and Clinical Pharmacology of the University of Freiburg and project head in Transregional Collaborative Research Center 152, “TRiPs to Homeostasis: Maintenance of Body Homeostasis by Transient Receptor Potential Channel Modules,” coordinated at LMU Munich.



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Auswertung.jpg Distribution of TPC channels (marked red) in kidney cells. Source: AG Klugbauer / University of Freiburg








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